Multifaceted Casr

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Project News

ESRs teaching to pupils at the Vienna International School

The ESRs based in Vienna, Abhishek and Samawansha took the students through basic biology lessons focussing on their research on colorectal cancer. Practical demonstrations to understand techniques of protein measurement and function were performed.

Last Updated on Thursday, 10 July 2014 13:04

Upcoming news: the second CaSR symposium is coming

Save the date for the 2nd International Symposium on The Calcium Sensing Receptor (CaSR)

March 3 – 4, 2015 Omni Hotel, San Diego, California, USA

Further Information

Last Updated on Tuesday, 24 June 2014 09:12

Prof. Raj Thakker elected as Fellow of the Royal Society

It was a great pleasure for us all to congratulate a PI Member of our ITN, Prof Raj Thakker, on the occasion of his election to be a Fellow of the Royal Society. Thus, a long overdue omission has been corrected.


Professor R.V. Thakker FMedSci FRS

May Professor of Medicine, University of Oxford


For those who might not recognize the significance and gravitas of such an Election, it must be added that, this is the highest science honour and recognition that can be bestowed upon a scientist in the UK. The Royal Society looks back on over 350 years of history; it is the foremost independent scientific academy, learned society in the UK. The Royal Society elects its own Fellows (members), currently less than fifteen hundred, solely on their scientific merit.

(Andrew Hollo-Tas)


Raj’s research has made significant contributions to endocrinology and metabolism, and especially to our understanding of the pathophysiology of parathyroid and kidney disorders that affect calcium homeostasis. His research at the basic science and clinical interface, has resulted in seminal discoveries of genes, with mechanistic insights at the molecular, cellular and physiological levels, that include: identification of functional pathways of calcium-sensing, through characterisation of mutations of the calcium-sensing-receptor, a G-protein coupled- receptor (GPCR), and components of its signalling pathway such as G-protein-alpha-11 subunit (Gα11) and adaptor-protein-2-sigma-subunit (AP2σ), which regulates GPCR endocytosis; and defining new parathyroid and kidney disorders that have established a molecular-based taxonomy with important biological insights into the development of syndromic and non-syndromic forms of parathyroid tumours, as well as the syndromic and non-syndromic forms of hypoparathyroidism and renal tubular physiology of calcium homeostasis. His clinical application of these advances has had a major impact on the diagnosis and treatments for endocrine and renal disorders.

Last Updated on Thursday, 22 May 2014 10:33

Martin Schepelmann is a doc!

Earlier this month, our Cardiff based ESR, Martin Schepelmann has been awarded his doctorate. He has survived this ordeal, that took 3 hrs. and 7 minutes, with flying colours. Thus he became the first of our ESRs who is now a PhD.

We are all proud of Martin. Well deserved congratulations to him.

(Andrew Hollo-Tas)

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Multifaceted CaSR is a Marie Curie Action
funded by the European Commission
under the 7th Framework Programme